The biology behind
the platform.

FluoSphera’s technology is rooted in research on cell encapsulation, tissue organization, and multi-tissue systems biology. Here is how the platform works.

core technology

Capsule design.

Microtissues in colour-coded orange, blue and purple droplets with green and pink fluorescent clusters

Each tissue is encapsulated in a color-coded hydrogel shell that maintains 3D structure, separates tissues, and enables soluble factor exchange to mimic systemic tissue communication. Capsules also control spheroid size and support non invasive tissue identification.

platform principles

Six capabilities,
one system.

O1

Compartmentalization

Microtissues that are organ-like, controlled in size, and allowing biochemical communication.

02

Recognition

Capsules enables non-invasive colour-coding identification of tissues without cell labelling.

03

Sensitivity

Human-relevant in vitro readouts calibrated to detect drug effects across complex biological profiles.

04

Multiplexing

High-content screening works with standard consumables and instruments.

05

Analytical precision

Single-organoid spatial positioning supports unbiased tracking across treatment duration.

06

Tissue sorting

Post-assay tissue sorting enables downstream genomic, proteomic, and transcriptomic profiling.

Peer-reviewed evidence.

High value studies built around real biological 
and development decisions.

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lab chip

2016

A 3D printed microfluidic device for production of functionalized hydrogel microcapsules for culture and differentiation of human Neuronal Stem Cells (hNSC)

Alessandri K., Feyeux M.,…, Roux A. et al

1 hours

Developmental Cell

2020

Buckling of an Epithelium Growing under Spherical Confinement

Trushko A, Di Meglio I, …, Roux A et al.

1 hour

partnership models

Predictive biology

Curious how it applies to your research with guidance tailored to your biological context.

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