Predict the therapeutic
index with integrated
profiling.

Evaluates efficacy, safety, and liver-driven drug effects in one integrated system, enabling more informed dose and lead optimization decisions.

request a study

request a study

Download overview

Download overview

Decorative background for the FluoScore sectionMicrotissues in colour-coded droplets with green and pink fluorescent cell clusters

what FluoScore delivers

Structural efficacy & toxicity

General readouts

Live/dead readouts generated per tissue type.

Functional efficacy & toxicity

Tissue-specific markers

Readouts such as albumin secretion, contractility, or barrier function depending on the tissues included.

DMPK-Tox

Liver metabolism integration

Evaluate how liver metabolism reshapes efficacy and safety profiles.

Dose finding

Dose-response across safety and efficacy

Create dose-response curves across tissues to identify the most favorable therapeutic index.

case studies

Seeing it work
in practice.

FluoSphera’s technology is rooted in research on cell encapsulation, tissue organization, and multi-tissue systems biology. Here is how the platform works.

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see more

FLUOSCORE

Oncology

Liver + Breast cancer

DMPK

+

Finding the Right Dose in a Metabolically Competent System

FLUOSCORE

Oncology

Liver + 2 Cancer types

DMPK Tox

+

Uncovering liver-dependent efficacy and hepatotoxicity of a prodrug

How we profile
your drug.

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Study design consultation.

We define the tissues, treatment strategy, and readouts around your decision-making needs.

01020304

Tissue
preparation.

Colour-coded tissues are prepared for each tissue type in the study panel.

01020304

Compound treatment 
& imaging.

Microtissue spheroids with green fluorescent puncta, some highlighted in cyan

High-content imaging captures phenotypic data across tissues and organoids.

01020304

Efficacy testing
report.

Microtissue spheroids stained magenta and cyan with green fluorescent puncta

You receive a structured data package with efficacy, safety, 
and DMPK-Tox interpretation.

partnership models

Predictive biology

Evaluate safety and efficacy with integrated metabolism for earlier development decisions.

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